Sunday, October 6, 2019

Leadership Assignment Example | Topics and Well Written Essays - 1000 words - 1

Leadership - Assignment Example I lead my ensuring that the people in my team are driven, motivated and satisfied. This would then help ensure that the task is completed on time. Considering the Leadership Grid by Blake and Mouton, I would say that my leadership styles is similar to that of a team manager. I scored 58% in task and 78% in people, this places me in the position highlighted below: My main concern always has been to ensure that the people in my group are happy and motivated. I collaborate with my friends and classmates when in a team. My first aim is to create cohesiveness in the group and then I move forward to define an action plan. Whenever I am made the leader of a group, I do not move towards the task at hand. I make sure the team members know each other and then we decide together the roles of each team member based on their area of expertise. I ensure that my team is satisfied with the task they are given so that they are comfortable and motivated towards the task. I believe that the team management style offers the most advantages. This is because it focuses more on the people. It is these people who are given the task of making the team successful. This style ensures motivated people who take ownership of the task given to them. The motivated people in the people enjoy working together and for the team. This then results in improved results and highly decreases the chances of team failure. Team members take responsibility of the team in their own ways. In this style, the conflicts are resolved in the open. It is inevitable that conflict will arise in a team but the team management style works on getting the conflict resolved through the participation of the team members. The people within the team feel valued and therefore are willing to resolve conflict together. This management style is particularly effective when the members in the group are skilled but need motivation. The team management style would be really suited for teams where

Friday, October 4, 2019

Operations Management Essay Example | Topics and Well Written Essays - 500 words

Operations Management - Essay Example All these are issues that would be beyond the controllable limits of the parent company, thereby making the business operations vulnerable to the ever-changing international scenario. A good example here would be of the current banning of online gambling in the US due to passing of new legislature by the Congress. This law inhibits the payments from banks and credit cards to be made to gambling sites and punters. Now sites based in other countries would be gravely affected by this drastic change in their operations, while incidentally, they have no control over the circumstances. Though there are strong rumors that international site owners paid millions of dollars to Washington lobbyists to get this stopped, yet the inevitable happened. Hence, this issue single handedly has changed the direction of the future of many sites. The basic element of economics being at the forefront always, one would go by the notion of demand and supply. However, being novel product, even though a dire need for the product may not be there, yet the demand for it would have to be created. And the crucial word here is 'customer'.

The Man at the Well Essay Example for Free

The Man at the Well Essay Some say it’s not what we do but what we don’t do that can truly define who we are. In the tenth chapter, â€Å"The Man at the Well†, from Tim O’Brien’s memoir, If I die in a Combat Zone, O’Brien manages to portray one of the most powerful messages throughout his entire journey. It’s about American ignorance, the inability to help those in need, the true meaning of humanity and whether we, as a population, are capable to break down barriers and walls that we, ourselves, have constructed. â€Å"A blustery and stupid soldier, blond hair and big belly, picked up a carton of milk and from fifteen feet away hurled it, for no reason, aiming at the old man and striking him flush in the face. The carton burst. Milk sprayed into the old man’s cataracts. He hunched foreword, rocking precariously and searching for his balance. He dropped his bucket. His hands went to his eyes then dropped loosely to his thighs. His blind gaze was fixed straight ahead, at the stupid soldier’s feet† (Page 100). O’Brien’s language it’s purposefully proposed and constructed to paint one of the most vivid images in the whole memoir. He creates a scene which the reader’s innovative mind engulfs and produces it into one of the most captivating and heart wrenching pictures easily shown like a movie in our own heads. His undeniable choice of descriptive words can’t help but have the effect of a film-like image flowing through the reader’s imagination. O’Brien uses this carefully disguised writing technique to ultimately grasp the hearts of his followers and use their sacrificing vulnerability to engrave a philosophical idea in their minds such as humanity’s opinion of right and wrong. â€Å"The Man at the Well† produces a foundation of shame and disbelief to think that a human being, an American soldier who is looked up to by children, Vietnamese and American, can fabricate such a hurtful scene. The audacity to even act out the horror and hate is appalling to any reader it makes he or she question the motives of several American soldiers and whether or not their morals are politically correct. It is a fine line between what is right and wrong there is little gray in a situation such as this. It’s clear the anecdote was an act of hatred. There was no question to whether the ignorance of the â€Å"stupid soldier† was right it was far past right. However why then, did no one do or say anything? Instead an audience watched as a man, a blind and elderly man, who voluntarily was helping them, suffered from one man’s intolerable actions. People are afraid and that fear creates a boundary. It changes people’s beliefs and ideas one thought always to be right and those ideas could change in an instance with the doubt fear carries. People come to a crossroads in their lives; where what they once thought their morals were, what they once thought they would stand up for is no longer because fear created a wall a wall that is unbearable to take down. It is a wall built in front of different people however sharing a common sense of right and wrong. These people cannot see past their own selfish fear to solve a crisis outside of themselves. If just a few attempted to demolish this imaginary roadblock the outcome could be greatly beneficial, however, it’s impossible to achieve unless people step outside of themselves and into a world they desire. The chapter argues one’s sense of humanity and the pressure that people feel and sometimes are burdened by. However, O’Brien places himself, as an author, in a position which he attempts to break down the wall. He asks you, â€Å"What is and what is not right? What are you going to do? Stand there and watch? Or are you going to do something about it?† I found the section powerful, moving and inspirational, and even more so if those who did answer his underlying questions, answered with an optimistic, â€Å"yes we can do this† point of view.

Thursday, October 3, 2019

Treatments for Hormone Sensitive Breast Cancer

Treatments for Hormone Sensitive Breast Cancer Rae Broz Oestrogen inhibiting Tamoxifen Citrate; an Antineoplastic Agent used to Treat Hormone Sensitive Breast Cancer The Hormone Oestrogen (E) fuels female breast growth production at puberty. Within the breast of mature women, there are milk ducts called lobes which branch out to form lobules or acinus. Together, these are called the terminal lobular unit (TDLU) (Bullock, 2013, pp. 917-918). Due to the various hormonal cycles that happen during a woman’s lifetime including, but not limited to child birth, Oestrogen and Progesterone levels are continuously fluctuating causing constant remodelling of the breast tissue. For example, menstruation causes the breast tissue to become increasingly vascular and encourages acinar tissue and ductal growth. Ancinar tissue converts to secretory glands through the release of progesterone at the luteal stage of the menstrual cycle. At this stage the terminal ducts are also dilated. (Craft. J, 2011, p. 951) Mitotic stem cell division is increased within the TDLU during these stages leading to the development and renewal of the epithelial lining, increasing the chance of cell mutations in the TDLU an area where the majority of breast cancer (BC) occur (Craft. J, 2011, p. 983). Studies show a positive sign of hormone sensitive BC is the increased amount of Oestrogen receptors (ERÃŽ ±). The more ErÃŽ ±s in the affected cells, the greater affinity with E, therefore cell reproduction rises, leading to faster BC cell replication (Patani, 2014). A benign tumor within the breast will remain localized and closely resembles normal epithelium cells within the tissue. Growth is at a slow rate within the TDLU, unlike a malignant (cancerous) tumor. The malignant tumor grows rapidly differentiating from the normal epithelial cell. It invades other tissue space and nearby blood and lymph vessels explaining why BCs easily spread into the lymphatic system and other areas of the reproductive system. Risk factors affecting hormone sensitive breast cancer development in women are Post-menopausal obesity and the woman’s age at the birth of her first child, as connections between older mothers and obese post-menopausal women to ERÃŽ ± positive BC have been discovered (Yager Davidson, 2006). Tamoxifen Citrate (Trans-1-[4- (2-dimethylaminoethoxy) phenyl] 1, 2 -diphenyl-1 –butene) is a non-steroidal drug and an antineoplastic agent called a selective estrogen receptor modulator (SERM) (Marrero-Alonso et al., 2013). It is recommended as part of the treatment of hormone sensitive breast cancer due to its affinity with ERÃŽ ± acting as an antagonist to E, slowing cell division within the breast consequently stopping the progression of the BC (Bryant, 2011, p. 822). Tamoxifen is given orally, absorbed in the gastro intestinal tract and metabolized in the liver by the enzymes CYP-450, 2D6 and 2C9. (Mandlekar, 2000 #20) Metabolites, produced are the ERÃŽ ± receptor binding 4-hydroxytamoxifen (OHT) and N-desmethyltamoxifen (DMT). Both have anti Oestrogen affects very close to their parent drug and cause apoptosis of BC cells. After dosing, various serum levels of Tamoxifen and metabolites were found within the lungs, liver ovaries and the endometrium and corpes luteum of the uterus, also in metastases within the brain and pancreas (Health Communication, 2004). Levels peak in about 3-6hours post a 10mg dose and reach a steady state around 4 weeks of therapy. They bind to albumin and are excreted mainly in the faeces so have a long half-life 5-7 days for Tamoxifen and 10-14 days for DMT (Health Communication, 2004). Due to the metabolism of Tamoxifen and its metabolites, there is a risk of serum accumulation in prolonged treatment and or patients with poor hepatic function dosing regimens major need intermittent adjustment according to serum level findings. (Health Communication, 2004). Phenytoin lowers Tamoxifen metabolism and should therefore not be used concurrently with Tamoxifen for extended periods of time unless a therapeutic drug (Endoxifen) monitoring strategy is utilized as Tamoxifen will lose effectiveness. (Gryn, Teft, Kim, 2014). It has been found that Tamoxifen treatment in postmenopausal women is beneficial in reducing calcium loss by reducing apoptosis of osteoclasts thus sustaining bone density (Nakamura et al., 2007). This unfortunately is not the case in premenopausal women; in these cases osteoporosis is often increased with the use of Tamoxifen, dependent on whether chemotherapy had caused amenorrhea or not (Vehmanen, Elomaa, Blomqvist, Saarto, 2006). Tamoxifen use has been linked to increased episodes of deep vein thrombosis (VTE) in women using the drug in breast cancer prevention treatment (Decensi et al., 2005). Finally patients receiving Tamoxifen treatment for breast cancer long term ( > five years) are at greater risk of mortality from endometrial cancer than those who did not receive Tamoxifen (Jones et al., 2012). Word count: 687 Reflection I hope I have created a better assignment this time round. I found the tutorial held on the 29/4/2014 very helpful as was the typed feedback sheet. I printed the latter out and sat it beside me while I typed out my assignment, along with the rubric and learning outcomes from the subject outline, referring to them often. The handwritten feedback was a little harder to decipher but I managed ok. My suggestion would be to type in an alternate colour e.g. Red for the feedback remarks on the actual assignment. I have learnt a lot from this assignment both about the subject and myself. I have incorporated more information into this assignment and have not included any quotes or paraphrasing from any of the texts I have used. The only similarities shown in turnitin were from my previous assignment. I have to say even with the setback I have enjoyed it. Word count: 151 References Bryant, B. a. K., K. (2011). Pharmacology for health professionals. Chatswood, NSW, Australia: Elsevier. Bullock, S. a. H., Majella. (2013). Principles of Pathophysiology. Frechs Forest, NSW, Australia: Pearson. Craft. J, G. C. a. t. A. (2011). Understanding Pathophysiology. Chatswood, NSW, Australia: Elsevier. Decensi, A., Maisonneuve, P., Rotmensz, N., Bettega, D., Costa, A., Sacchini, V., . . . Veronesi, U. (2005). Effect of tamoxifen on venous thromboembolic events in a breast cancer prevention trial. Circulation, 111(5), 650-656. doi: 10.1161/01.cir.0000154545.84124.ac Gryn, S. E., Teft, W. A., Kim, R. B. (2014). Profound reduction in the tamoxifen active metabolite endoxifen in a patient on phenytoin for epilepsy compared with a CYP2D6 genotype matched cohort. Pharmacogenetics and Genomics, Publish Ahead of Print, 10.1097/FPC.0000000000000051. Health Communication, N. (2004). MIMS Online. from Health Communication Network Jones, M., van Leeuwen, F., Hoogendoorn, W., Mourits, M., Hollema, H., van Boven, H., . . . Swerdlow, A. (2012). Endometrial cancer survival after breast cancer in relation to tamoxifen treatment: Pooled results from three countries. Breast Cancer Research, 14(3), R91. Marrero-Alonso, J., Morales, A., Garcà ­a Marrero, B., Boto, A., Marà ­n, R., Cury, D., . . . Dà ­az, M. (2013). Unique SERM-like properties of the novel fluorescent tamoxifen derivative FLTX1. European Journal of Pharmaceutics and Biopharmaceutics, 85(3, Part B), 898-910. doi: http://dx.doi.org/10.1016/j.ejpb.2013.04.024 Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., . . . Kato, S. (2007). Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell, 130(5), 811-823. doi: 10.1016/j.cell.2007.07.025 Patani, N. a. M. L. A. (2014). Understanding response and resistance to oestrogen deprivation. Molecular and Cellular Endocrinology, Volume 382(1), 683-894. Vehmanen, L., Elomaa, I., Blomqvist, C., Saarto, T. (2006). Tamoxifen treatment after adjuvant chemotherapy has opposite effects on bone mineral density in premenopausal patients depending on menstrual status. J Clin Oncol, 24(4), 675-680. doi: 10.1200/jco.2005.02.3515 Yager, J. D., Davidson, N. E. (2006). Estrogen Carcinogenesis in Breast Cancer. New England Journal of Medicine, 354(3), 270-282. doi: doi:10.1056/NEJMra050776

Wednesday, October 2, 2019

Dmitri Shostakovich and the Soviet State Essay -- Soviet History

Dmitri Shostakovich was one of the most celebrated composers of the 20th century. He achieved fame, but with much hardship along the way. He was censored and threatened with not only his life but that of his wife and children by playing the role of a public figure in Soviet Russia. The question is was he a committed communist or a victim? The events in his life, good or bad, shaped the music that he created and led to one of the greatest symphonies of the 20th century, his Fifth Symphony. Born in Saint Petersburg, Russia on September 25, 1906, Shostakovich was the second of three children born to Dmitri Boleslavovich Shostakovich and Sofiya Vasilievna Kokoulina. His father was of Polish descent but both his parents were Siberian natives. Dmitri was a child prodigy as a pianist and composer. He began taking piano lessons from his mother at the age of nine. He displayed an incredible talent to remember what his mother had played at the previous lesson and would get caught pretending to read the music, playing the music from his last lesson instead of what was placed in front of him. In 1919, at the age of thirteen, he was allowed to enter the Petrograd Conservatory in Saint Petersburg and studied piano with Leonid Nikolayev. Because the conservatory was poorly funded, it did not have heat; the students had to wear coats, hats and gloves constantly only taking off their gloves when composing. Because of these poor living conditions Dmitri developed tuberculosis of the lymph glands in spring 1923 and had to have an operation. Nevertheless, he completed his final piano examinations at the conservatory in June with his neck still bandaged. Shostakovich, though very intelligent and talented, was seen as immature in his fin... ...alled. Works Cited †¢ Burkholder, J. Peter, Donald Jay Grout, and Claude V. Palisca. A history of western music. 8th ed. New York: W. W. Norton, 2010. Print. †¢ Fanning, David. Shostakovich studies. Cambridge: Cambridge University Press, 1995. Print. †¢ Hurwitz, David, and DmitriÄ ­ Dmitrievich Shostakovich. Shostakovich symphonies and concertos: an owner's manual. Pompton Plains, N.J.: Amadeus ;, 2006. Print. †¢ Norris, Christopher. Shostakovich, the man and his music. Boston: M. Boyars, 1982. Print. †¢ Volkov, Solomon, and Antonina W. Bouis. Shostakovich and Stalin: the extraordinary relationship between the great composer and the brutal dictator. New York: Knopf, 2004. Print. †¢ David Fanning and Laurel Fay. "Shostakovich, Dmitry." Grove Music Online. Oxford Music Online. 14 Apr. 2012 .

Film Essay -- Research Papers Movies Religion Papers

Film Since its introduction to America and the world, film has become one of the most important and popular cultural mediums ever (Marsh 33). Ever since the motion picture industry began, the role of Jesus Christ has been used numerous times in different ways. These portrayals of Jesus in film have varied in showing either a traditional image, pertaining to the gospels, or one more unconventional, usually based on someone else's interpretation. Both of these different ways of showing Jesus and his life have greatly influenced people’s image of him (Brunstad 145). Because of the movies' portrayals of Jesus, his differing image has also been shown as more human, usually when Jesus is unconventional, or more divine. The portrayal of Jesus Christ, from Ben-Hur to The Passion of the Christ, focuses too much on either his human aspect or his divine aspect, but has never met the correct depiction of a believable God-man. Jesus Christ shown as a God-man is central to Christian beliefs. In Christian culture Jesus is understood to be both fully divine and fully human at the same time. Because of this idea, the attempt has been made by several films to show Jesus in this way, but has never been achieved. The movies that will be discussed in this paper came out between 1959, after Ben-Hur, and 2004, before The Passion of the Christ. They are as follows, in chronological order of when released: Ben-Hur, King of Kings, The Greatest Story Ever Told, The Gospel According to Saint Matthew, Jesus Christ Superstar, Jesus of Nazareth, The Last Temptation of Christ, and The Passion of the Christ. Ben-Hur came out in 1959. It was directed by William Wyler. The role of Jesus was played by Claude Heater. This movie de... ... of Motion Picture Arts and Sciences. 15 March 2004. 25 Apr 2004 . Grimshaw, Michael. â€Å"Sexless Piety or a Man’s Man? Notes on the cinematic representation of Jesus.† Journal of Beliefs and Values 20 (1999): 149-161. Hittinger, Russell and Elizabeth Lev. â€Å"Gibson’s Passion.† First Things: A Monthly Journal of Religion and Public Life 141 (2004): 7-9. Kinnard, Roy and Tim Davis. Divine Images: A History of Jesus on the Screen. New York: Carol, 1992. Marsh, Clive and Gaye Ortiz, eds. Explorations in Theology and Film. Oxford: Blackwell, 1997. Medved, Michael. Hollywood Vs. America: Popular Culture and the War on Traditional Values. New York: HarperCollins, 1992. Stern, Richard C, Clayton N Jefford, and Guerric DeBona,. Savior on the Silver Screen. New York: Paulist, 1999. Turner, Matthew Paul. â€Å"Jesus in Living Color.† Christian Single 26 (2004): 40.

Tuesday, October 1, 2019

Examine the different ways in which ‘good’ is used in meta-ethics Essay

a) â€Å"Examine the different ways in which ‘good’ is used in meta-ethics.† Meta-ethics is the study of the meaning of moral language. It describes presuppositions and language of morality. There are a number of different ethical theories for the meaning of good used in meta-ethics. The four main headings under which most acceptable theories can fit under in some shape or form. These are Ethical Naturalism (or Definism), Intuitionism, Emotivism and Presciptivism. Definism theory states that all ethical statements are similar to non-ethical statements and can, therefore, be approached in the same way. In the same way that we can verify a scientific fact, ethical naturalism theory states that we can verify an ethical statement. They are both prepositional. Definism states that ethical statements are just a type of short hand for more complex propositions. So therefore, in terms of Ethical Naturalism, if I were to use the term ‘good’ in a number of examples, it would just be a ‘summary’ word to sum up all the other words I wish to have incorporated into my sentence. For example, in the sentence: â€Å"I am good at football,† the word good is used to mean ‘skilled’ or ‘talented.’ This does not mean that ‘good’ means ‘skilled’ or ‘talented’, but simply that both of these words are incorporated in the single use of ‘good.’ In another sentence, ‘good’ could be used as a short hand for a completely different set of words. In the sentence, â€Å"It is good to see you,† ‘good’ is used to mean ‘pleasant’, ‘nice’ or ‘heart warming.’ Again this does not mean that ‘good’ means ‘pleasant’ or ‘nice’, but simply that both these words are incorporated in the single use of ‘good.’ A contradictory theory to Definism is Intuitionism. Intuitionism states that ‘good’ is indefinable. Intuitionism also holds that basic moral truths are objective and stand independently of what people my fell or think. Intuitionism holds that we should pick out our moral principles through what we think or feel. There is no definition of good that can always hold true. For example, if someone were to define good as ‘pleasing’, an Intuitionist would respond by pointing out that not all pleasing things are good. A similar theory to Intuitionism is Emotivism. An Emotivist believes that moral judgements simply express our feelings on a subject. If someone were to claim something was ‘good’, an Emotivist would see this as an emotional exclamation, not a truth claim, and would take it to mean that the person approves of the thing/action/person etc. Another fairly similar theory is Prescriptivism. Prescriptivists believe that in using moral language such as ‘good/bad’ or ‘right/wrong,’ we are simply prescribing our opinions. In other words were are saying, ‘do this, and let everyone do the same in the same situation.’ Therefore, if someone were to say ‘giving to charity is good,’ what he or she is really saying is ‘you ought to give to charity.’ This again, means that ‘good’ not used as a universal truth, but in this case it is used as a universal prescription. In summary: in Definism, the term ‘good’ is simply a ‘short hand’ for more complex propositions that apply to that particular example. In Intuitionism holds that good in indefinable and therefore has no universal meaning. Emotivists believe when we use the term ‘good or make other moral judgements, we are simply expressing our feelings. So, therefore, if I say something is ‘good,’ this is simply an exclamation and therefore cannot be true or false and cannot be reasoned upon. Lastly, Prescriptivism holds that when we say something is ‘good’ we are prescribing a particular opinion and making it known to other that we feel they should do the same. b) â€Å"Anything people approve of must be good. Discuss†¦Ã¢â‚¬  The response to this question depends on how we define the term ‘good.’ Can we loosely define ‘good’ as moralistic? There is a common theory that believes that our morals our simply a product of our culture and background. Therefore, there will be different moral codes in different societies. If each individual society has equal validity, it must be agreed that there can be no universal moral code. This theory is called Cultural Relativism. Cultural Relativism therefore holds that ‘good’ means ‘socially approved.’ Therefore if we rearrange the above statement, replacing the word ‘good’ with the Cultural Relativist’s definition, we find ourselves looking at a slightly odd sentence which looks as follows: â€Å"Anything that people approve of must be socially approved†. Now there are two ways to interpret this sentence. The first would be to question the number of people included in the generalization of the word ‘people.’ If the sentence is intended to mean, â€Å"if anybody approves of something, it must be socially approved†, then the statement is not true. However, we can also take the sentence to mean, â€Å"If the majority of people within a society approve of something, then it is said to be socially approved.† If we swap ‘good’ back into the sentence we end up with a statement that looks like this: † if the majority of people within a society approve of something then it is good.† Thus we have formed the central principle of Cultural relativism. In terms of the other theories that define ‘good’, only one can be applied. Definism would argue that the statement is simply a short hand for more complex propositions. So in this case, ‘good’ is used to mean ‘beneficial’ or ‘correct.’ Since this is possibly true, Ethical naturalists would have a fairly strong argument here. Emotivism, Intuitionism or Prescriptivism cannot really apply here as they are all subjective and based on opinion and in this case good cannot be used an exclamation of opinion.

Glass Ceiling Essay Example for Free

Unattainable rank Essay Unattainable rank is a term that portrays the fake level, past which ladies and different minorities are denied t...